Per Kogner Selected Research

L-melphalanyl-p-L-fluorophenylalanine ethyl ester

9/2007

The novel melphalan prodrug J1 inhibits neuroblastoma growth in vitro and in vivo.

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Per Kogner Research Topics

Disease

93	Neuroblastoma 01/2022 - 02/2002
72	Neoplasms (Cancer) 04/2022 - 02/2002
9	Medulloblastoma 04/2022 - 10/2008
6	Inflammation (Inflammations) 06/2018 - 11/2003
3	Carcinogenesis 01/2016 - 12/2008
3	Pheochromocytoma 04/2014 - 06/2005
3	Residual Neoplasm 11/2011 - 04/2003
3	Brain Neoplasms (Brain Tumor) 01/2010 - 02/2002
3	Ganglioneuroma 01/2007 - 02/2002
2	Lymphoma (Lymphomas) 01/2019 - 02/2015
2	Neuroendocrine Tumors (Neuroendocrine Tumor) 03/2018 - 06/2005
2	Teratoma (Teratoid Tumor) 01/2018 - 04/2014
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2018 - 11/2009
2	Infections 01/2017 - 07/2010
2	Chromosome Aberrations (Chromosome Abnormalities) 03/2016 - 01/2012
2	Lung Neoplasms (Lung Cancer) 02/2015 - 11/2009
2	Disease Progression 01/2011 - 01/2003
2	Necrosis 10/2005 - 12/2004

Drug/Important Bio-Agent (IBA)

20	Proteins (Proteins, Gene)FDA Link 01/2022 - 08/2004
12	DNA (Deoxyribonucleic Acid)IBA 01/2017 - 04/2003
11	Messenger RNA (mRNA)IBA 01/2022 - 01/2003
10	Pharmaceutical PreparationsIBA 12/2019 - 09/2003
8	Dinoprostone (PGE2)FDA Link 04/2022 - 10/2008
8	Anaplastic Lymphoma KinaseIBA 01/2022 - 12/2008
8	Biological ProductsIBA 09/2012 - 11/2003
6	Small Interfering RNA (siRNA)IBA 01/2022 - 10/2008
6	Phosphotransferases (Kinase)IBA 01/2022 - 01/2010
6	Prostaglandin-E SynthasesIBA 01/2020 - 10/2008
6	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2020 - 05/2006
6	LigandsIBA 07/2019 - 02/2002
5	RNA (Ribonucleic Acid)IBA 04/2022 - 10/2011
5	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 05/2006 - 10/2004
4	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 04/2022 - 05/2006
4	Protein Isoforms (Isoforms)IBA 03/2021 - 11/2010
4	RetinoidsIBA 01/2017 - 04/2003
4	Cisplatin (Platino)FDA LinkGeneric 01/2017 - 10/2004
4	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2017 - 04/2003
4	EnzymesIBA 06/2015 - 02/2007
4	Diclofenac (SR 38)FDA LinkGeneric 06/2015 - 10/2004
4	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2012 - 10/2004
4	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 01/2012 - 10/2004
4	Celecoxib (Celebrex)FDA Link 10/2011 - 10/2004
4	Peptides (Polypeptides)IBA 01/2006 - 02/2002
4	Protons (Proton)IBA 10/2005 - 10/2004
4	Choline (Choline Chloride)IBA 10/2005 - 10/2004
3	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 10/2021 - 03/2013
3	Long Noncoding RNAIBA 01/2021 - 11/2014
3	Vincristine (Oncovin)FDA LinkGeneric 01/2020 - 07/2010
3	rho-Associated KinasesIBA 12/2019 - 03/2016
3	CalciumIBA 11/2017 - 01/2012
3	Etoposide (VP 16)FDA LinkGeneric 01/2017 - 10/2004
3	LipidsIBA 06/2015 - 10/2005
3	Transforming Growth Factors (Transforming Growth Factor)IBA 07/2013 - 03/2013
3	Phosphatidylinositols (Phosphatidylinositol)IBA 04/2013 - 01/2010
3	Prostaglandins EIBA 01/2012 - 10/2008
3	ProstaglandinsIBA 01/2012 - 10/2008
3	Docosahexaenoic AcidsIBA 04/2011 - 05/2006
3	Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA 12/2008 - 01/2003
3	Arachidonic Acid (Vitamin F)IBA 10/2008 - 10/2004
3	Irinotecan (Camptosar)FDA LinkGeneric 02/2007 - 10/2004
3	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 05/2006 - 10/2005
3	Galanin Receptors (Galanin Receptor)IBA 01/2006 - 02/2002
3	GalaninIBA 01/2006 - 02/2002
2	RadiopharmaceuticalsIBA 01/2022 - 01/2007
2	NSC 652287IBA 09/2021 - 09/2013
2	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 01/2020 - 10/2008
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2019 - 12/2008
2	Genetic Markers (Genetic Marker)IBA 03/2018 - 08/2009
2	CytokinesIBA 11/2017 - 03/2013
2	ChemokinesIBA 11/2017 - 01/2016
2	Cytostatic AgentsIBA 02/2017 - 12/2004
2	Differentiation AntigensIBA 01/2017 - 03/2009
2	Biomarkers (Surrogate Marker)IBA 01/2017 - 11/2014
2	Aurora KinasesIBA 01/2017 - 09/2013
2	Melphalan (Alkeran)FDA LinkGeneric 01/2017 - 09/2007
2	Carboplatin (JM8)FDA LinkGeneric 01/2017 - 07/2010
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2017 - 07/2010
2	CateninsIBA 03/2016 - 11/2015
2	Complementary DNA (cDNA)IBA 03/2016 - 01/2016
2	MicroRNAs (MicroRNA)IBA 01/2016 - 07/2011
2	4- (2- (2- hydroxycyclohexylamino)benzothiazol- 6- yloxy)pyridine- 2- carboxylic acid methylamideIBA 01/2016 - 01/2016
2	Macrophage Colony-Stimulating FactorIBA 01/2016 - 01/2016
2	MethyltransferasesIBA 11/2015 - 12/2004
2	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 06/2015 - 03/2009
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 04/2014 - 08/2009
2	Thromboxane A2 (A2, Thromboxane)IBA 07/2013 - 05/2013
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 07/2013 - 05/2013
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2011 - 08/2009
2	Arachidonate 15-Lipoxygenase (Arachidonate 15 Lipoxygenase)IBA 04/2011 - 03/2010
2	trichostatin A (A 300)IBA 02/2011 - 07/2008
2	Caspase 8 (Caspase-8)IBA 05/2008 - 12/2004
2	CaspasesIBA 03/2007 - 12/2004

Therapy/Procedure

31	Therapeutics 01/2022 - 03/2003
11	Drug Therapy (Chemotherapy) 02/2019 - 10/2004
4	Immunotherapy 11/2018 - 11/2003
3	Radiotherapy 01/2022 - 05/2017
2	Transplantation 01/2018 - 04/2014
2	Heterologous Transplantation (Xenotransplantation) 01/2016 - 04/2014
2	Combined Modality Therapy 01/2016 - 05/2013
2	Injections 03/2014 - 08/2006